How Does This Medicine Work?Camptosar belongs to a group of medicines known as topoisomerase I inhibitors. Topoisomerase I is an enzyme that helps relax DNA that has been overwound, which can occur when DNA is duplicating so cells can divide. It does this by breaking the DNA strand to relieve the strain and then rejoining the strand. Camptosar binds to topoisomerase I and prevents the enzyme from repairing the breaks in the DNA, and this causes the cell to die.
Is It Safe for Use in Children?Camptosar is not approved for use in children. At this time, it is not known whether this medication works in children. Talk with your child's healthcare provider about the particular benefits and risks of using Camptosar in children.
Can Older Adults Use Camptosar?Older adults can use this medicine. However, older adults appear to have a higher risk for certain side effects, such as diarrhea. Some older adults may need a lower starting dose, depending on the Camptosar dosing regimen used.
Off-Label Uses for CamptosarOn occasion, your healthcare provider may recommend this drug for something other than the uses discussed in this article. This is called an "off-label" use. Camptosar may be used off-label to treat other types of cancer, including but not limited to: