Colon Cancer Home > Side Effects of Capecitabine

Serious Side Effects of Capecitabine

Some side effects with capecitabine, while occurring infrequently, are potentially serious and should be reported immediately to your healthcare provider. These include, but are not limited to:
  • Depression (see Xeloda and Depression)
  • Signs of a blood clot, such as pain, swelling, or tenderness (especially in the legs)
  • Blood in the stool or coughing up blood (signs of gastrointestinal bleeding)
  • Very severe constipation, nausea, vomiting, or mouth sores
  • Severe pain or redness of the hands or feet
  • An increase in tumor size or appearance of new tumors
  • A fever or other signs of an infection (see Chemotherapy and Infections)
  • Signs of liver problems, such as yellowing of the whites of the eyes or skin, dark urine, and right upper abdominal (or stomach) pain.
  • Signs of an allergic reaction, including an unexplained rash, hives, itching, and unexplained swelling.

Less Common Side Effects of Capecitabine

Less common side effects of capecitabine occur in less than 5 percent of people taking the drug. Because these side effects are so uncommon, it can be difficult to tell whether they are actually caused by capecitabine or by factors unrelated to the medication.
Some of these rare side effects include, but are not limited to:
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
Other Articles in This eMedTV Presentation

Topics & Medications


Related Channels

eMedTV Links
Copyright © 2006-2019 Clinaero, Inc.

eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.

This site complies with the HONcode standard for trustworthy health information:
verify here.