Colon Cancer Home > Vectibix

Vectibix is a drug prescribed to help slow down the progression of colorectal cancer that has spread to other areas of the body. It is used when there is a certain protein present on the surface of the cancer cells. Side effects may include fatigue, skin reactions, and abdominal pain. This medication comes as a liquid that is administered intravenously every 14 days.

What Is Vectibix?

Vectibix® (panitumumab) is a prescription medication approved to treat colorectal cancer (cancer of the colon and rectum) that has spread to other areas of the body after treatment with other chemotherapy. It is only used in the treatment of cancer that has a certain protein, known as epidermal growth factor receptor (EGFR), on the surface of the cancer cells.
(Click Vectibix Uses for more information on this topic, including possible off-label uses.)

Who Makes This Medication?

Vectibix is manufactured by Amgen, Inc.

How Does Vectibix Work?

Vectibix works by binding to a certain receptor in the body called epidermal growth factor receptor (EGFR). EGFR is found on the surface of normal cells and some cancer cells.
Normally, certain proteins, such as epidermal growth factor, bind to EGFR and tell cells to grow. By binding to EGFR, Vectibix blocks these proteins from binding and slows down the growth of cancer cells. Vectibix does not cure cancer.

Clinical Effects

In clinical trials, Vectibix was shown to extend the amount of time until colorectal cancer progressed (got worse). In one study, people who received Vectibix had approximately 36 more days without further disease progression than people who did receive Vectibix. However, the medication did not appear to improve cancer symptoms or help people live longer.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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