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Stivarga Drug Interactions

Stivarga Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Stivarga is combined with any of the drugs listed above.
 
CYP 3A4 Inducer Medications
The liver breaks down Stivarga using enzymes known as CYP 3A4 enzymes, and some medications known as CYP 3A4 inducers can increase the activity of these enzymes. Thus, combining Stivarga with one of these drugs may decrease the level of Stivarga in your body. Stivarga should not be used with strong CYP 3A4 inducers.
 
CYP 3A4 Inhibitor Medications
The liver breaks down Stivarga using enzymes known as CYP 3A4 enzymes, and some medications known as CYP 3A4 inhibitors can decrease the activity of these enzymes. Thus, combining Stivarga with one of these drugs may increase the level of Stivarga in your body. Stivarga should not be used with strong CYP 3A4 inhibitors.
 
Warfarin
Taking Stivarga with warfarin may increase the risk for dangerous internal bleeding. Your healthcare provider may need to monitor you more closely, by checking your prothrombin time ("protime," or PT) and international normalized ratio (INR) more frequently, if you take these medicines together.
 

Final Thoughts

It is possible that not all Stivarga drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific interactions that may apply to you.
 
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