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Vectibix Side Effects

When Vectibix was studied in clinical trials, some of the most commonly reported side effects included skin reactions, fatigue, and nausea. Although some people may not experience any problems with this drug, most people will develop some type of reaction during Vectibix treatment. Some reactions can be potentially serious, such as difficulty breathing and changes in vision, and may require medical treatment.

An Introduction to Vectibix Side Effects

Just like any medicine, Vectibix® (panitumumab) can cause side effects. Not everyone who receives the medication will have problems. However, most people will experience some type of side effect during Vectibix treatment. Some side effects may be treated by your healthcare provider with other medicines.
(This article covers many, but not all, of the possible side effects with Vectibix. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects With Vectibix

Vectibix has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people who received Vectibix were carefully documented and compared to the side effects that occurred in a similar group of people who did not receive Vectibix. As a result, it was possible to see what side effects occurred and how often they appeared.
In these studies, the most common side effects of Vectibix included:
  • Skin reactions -- in up to 90 percent of people
  • Low blood magnesium levels (hypomagnesemia) -- up to 38 percent
  • Fatigue -- up to 26 percent
  • Infections around the toenails and fingernails -- up to 25 percent
  • Abdominal (stomach) pain -- up to 25 percent
  • Nausea -- up to 23 percent
  • Diarrhea -- up to 21 percent
  • Constipation -- up to 21 percent
  • Vomiting -- up to 19 percent.
Other common side effects, occurring in 3 percent to 15 percent of people, included but were not limited to:
  • Eye problems, such as:
    • Inflammation
    • Redness
    • Tearing
    • Irritation
  • Cough
  • Swelling of the arms, hands, legs, ankles, and feet
  • Sores and inflammation of the mouth
  • Problems with the toenails or fingernails
  • Growth of hair and eyelashes
  • Reactions to the infusion.
The majority of people in clinical trials experienced a skin reaction of some type, usually within the first two weeks of starting treatment. Reported reactions included:
  • Redness
  • An acne-like rash
  • Other rashes
  • Itching
  • Peeling skin
  • Cracking skin
  • Dry skin.
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Vectibix Medication Information

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