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Zaltrap Dosage

When treating colorectal cancer, Zaltrap dosing guidelines will be based on how much you weigh, how you tolerate the medicine, and other factors. This prescription drug is given as a slow injection into a vein once every two weeks. Treatment usually lasts until the cancer progresses or you develop serious side effects.

An Introduction to Dosing With Zaltrap

The dose of Zaltrap® (ziv-aflibercept) your healthcare provider recommends will vary, depending on:
  • Your weight
  • How you tolerate the medication.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

What Is the Recommended Zaltrap Dosage?

The standard recommended dose of Zaltrap for the treatment of colorectal cancer is 0.4 mg per kg body weight (about 0.18 mg per lb) once every two weeks. Treatment normally continues until the cancer progresses or severe side effects occur.
If you develop potentially serious side effects during treatment, your healthcare provider may recommend you temporarily stop using the medication until your side effects improve, and then restart you at a lower Zaltrap dosage. In some cases, the side effects may be severe enough that you need to stop the drug altogether.

General Information on Receiving Zaltrap

Some considerations to keep in mind during treatment with Zaltrap include the following:
  • This medication is usually given as a slow injection into a vein (an intravenous, or IV, infusion) once every two weeks.  
  • This medication is normally given by a healthcare provider in a healthcare setting, such as a hospital or clinic.
  • The Zaltrap dose is given slowly, over about one hour. If you will be receiving other chemotherapy medicines, you will normally be given Zaltrap first.
  • For this drug to work properly, it must be used as prescribed.
  • If you are unsure about anything related to your dosage of Zaltrap, please talk with your healthcare provider or pharmacist.
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